The Antonescu Lab
for fundamental and cancer cell biology

We are a cell biology laboratory interested in fundamental cellular processes that when disrupted contribute to cancer progression. We study a number of dynamic nanoscale molecular assemblies such as clathrin structures, receptor complexes , and lipid remodeling structures, which control signaling and membrane traffic. In turn, these regulate cell proliferation, growth and migration. We are interested in how these dynamic molecular assemblies are regulated by chemical, mechanical and metabolic cues, and how they can be therapeutically controlled for cancer treatment and targeted drug delivery.